Microelectronic design of a pseudo voltage clamp for a 0.18um CMOS-based mesoscale neural interface for intracellular in-vitro recording and stimulation

The need to understand how the brain works has sparked interest in electrode arrays to record neural signals. Intracellular recordings with nanoelectrodes that penetrate the cell allow better signal quality and additional functions such as voltage clamping to set the neuron's transmembrane voltage. The voltage clamp aims to facilitate the...

Electrical characterization of nanoparticle and protein networks

This thesis describes the research directed towards practical realization of an on-chip biosensing technology and that of understanding charge transport mechanisms in organic and biological nanoobjects. For this, silicon-based chips with metallic nanoelectrodes were fabricated using electron-beam lithography and metal evaporation. The final...

The use of STEM imaging to analyze thickness variations due to electromigration-induced mass transport in thin polycrystalline nanobridges

Scanning transmission electron microscopy (STEM) imaging is applied to analyze the electromigration-induced thickness variations of thin polycrystalline films, It is shown that a high angle annular dark field (HAADF) detector is required to minimize the effect of diffraction contact. A further reduction of the diffraction contrast can be...

Nanofabrication of electrodes with sub-5 nm spacing for transport experiments on single molecules and metal clusters