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Elders, Bente (author)Restrictions from the covid pandemic are lifted. However, the office remains changed, the hybrid way of working seems to stick. Employees want flexibility and choose when to work from home and when they work in the office. The norm of a hybrid work week is working three days in the office and two days from home. Resulting in office space that is...master thesis 2024
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Sheykhzadeh, Morteza (author), Ghasemi, Rohollah (author), Vandchali, Hadi Rezaei (author), Sepehri, A. (author), Torabi, Seyed Ali (author)Due to the outbreak of COVID-19 around the globe in the last few years, the need for pharmaceutical supply chains is felt more than before. However, increasing uncertainties along with unpredictable demand for products led to disruptions in supply chains when receiving requests from retailers. These disruptions not only affected the economic...journal article 2024
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Moradi, N. (author), Lopez Vazquez, C.M. (author), Hernandez, Hector Garcia (author), Proskynitopoulou, Vera (author), Vouros, Anastasios (author), Garagounis, Ioannis (author), Lorentzou, Souzana (author), Brdjanovic, Damir (author), van Loosdrecht, Mark C.M. (author)In recent decades, there has been a growing focus on the management and valorization of digestate, primarily driven by its nutrient-rich composition, which positions it as a promising resource for biofertilizer production. However, several countries still restrict the direct application of digestate due to its potential environmental hazard,...journal article 2024
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Ahmadi, Navid (author), Abbasi, Mona (author), Torabian, Ali (author), van Loosdrecht, Mark C.M. (author), Ducoste, Joel (author)We investigated the transformation of four pharmaceuticals (Diclofenac, Naproxen, Ibuprofen and Carbamazepine) in a moving bed biofilm reactor subjected to different COD/N ratios in four experimental phases. The shift from medium to high range COD/N ratio (i.e., 5:1 to 100:1) intensified the competition between heterotrophs and nitrifying...journal article 2023
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- Lopes Vieira, Mariana (author) master thesis 2022
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Hagenaars, Rosalie (author)This thesis explores the relatively large contribution of the product category ‘chemicals n.e.c.’ (chemicals not elsewhere classified) to the Dutch healthcare sector’s carbon and material footprint observed in previous studies. For this, an input-output study using SNAC-EXIOBASE data was performed. SNAC-EXIOBASE uses national statistics for the...master thesis 2022
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Marin, Nicoleta Mirela (author), Stanculescu, I.R. (author)The purpose of the research consists of: i) development of a new specific adsorption method for two anesthetic drugs, procainamide (PHA) and lidocaine (LID) from aqueous solutions on Amberlite XAD7HP polyester resin and ii) obtaining a high-performance new material, PHA respectively LID loaded resin, for As(V), Cd(II) and Pb(II) metallic ions...journal article 2022
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Keetels, G.H. (author), Godderis, L. (author), van de Wiel, B.J.H. (author)Background: Both influenza and SARS-CoV-2 viruses show a strong seasonal spreading in temperate regions. Several studies indicated that changes in indoor humidity could be one of the key factors explaining this. Objective: The purpose of this study is to quantify the association between relevant epidemiological metrics and humidity in both...journal article 2022
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- Zhang, Yongjun (author), Hu, Jiangyong (author), Nomngongo, Philiswa Nosizo (author), Wang, Qilin (author), Spanjers, H. (author) contribution to periodical 2022
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Dedehayir, Ozgur (author), Mäkinen, Saku J. (author), Ortt, J.R. (author)Despite their importance little is known about how innovation ecosystems come into existence. We address this gap through an historical case study Herceptin, a revolutionary drug developed for the treatment of ovarian and breast cancer, and the innovation ecosystem that emerged around this drug between 1978 and 1998. Through qualitative content...journal article 2022
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Doornenbal, Eline (author)The R&D productivity crisis is among the most pressing issues in the drug industry. The increasing costs and stable R&D outputs jeopardise the industry’s economic health, drug innovation, and the accessibility and affordability of medicines. The pharmaceutical R&D productivity problem is expected to be diminished due to...master thesis 2021
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GAL, Jean (author)Blockchain is an expanding technologythat offers benefits when applied to supplychain management. This distributed ledgertechnology is combined with supply chainsfor its intrinsic characteristics. For instance,traceability, immutability, and more arediscussed. In this paper, we first presentprivacy-related challenges encountered whenapplying...bachelor thesis 2021
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La Zara, D. (author)The majority of pharmaceutical products is made of solid powders. The morphology and surface characteristics of drug particles affect both their bulk behaviour, e.g., flowability, dispersibility and tabletability, in the manufacturing process of dosage forms as well as their bioavailability upon administration into the human body. For instance,...doctoral thesis 2021
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Roschangar, Frank (author), Li, Jun (author), Zhou, Yanyan (author), Aelterman, Wim (author), Borovika, Alina (author), Colberg, Juan (author), Dickson, David P. (author), Gallou, Fabrice (author), Sheldon, R.A. (author)The large and steadily growing demand for medicines combined with their inherent resource-intensive manufacturing necessitates a relentless push for their sustainable production. Pharmaceutical companies are constantly seeking to perform reliable life cycle assessments of their medicinal products and assess the true value of their sustainable...journal article 2021
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Amoroso, Rosa (author), Hollmann, F. (author), Maccallini, Cristina (author)DES are mixtures of two or more compounds, able to form liquids upon mixing, with lower freezing points when compared to the individual constituents (eutectic mixtures). This attitude is due to the specific hydrogen-bond interactions network between the components of the mixture. A notable characteristic of DES is the possibility to develop...review 2021
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La Zara, D. (author), Zhang, F. (author), Sun, F. (author), Bailey, Maximilian R. (author), Quayle, Michael J. (author), Petersson, Gunilla (author), Folestad, Staffan (author), van Ommen, J.R. (author)The wettability of pharmaceuticals is a key physical property which influences their dissolution rate, dispersibility, flowability and solid-state stability. Here, we provide a platform of surface nanoengineering methods capable of tuning the wettability of drug powders from high hydrophilicity to superhydrophobicity with drug loadings up to...journal article 2021
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Romolo, Francesco Saverio (author), Sarilar, M. (author), Antoine, Johann (author), Mestria, Serena (author), Strano Rossi, Sabina (author), Gallidabino, Matteo Davide (author), Soares de Souza, Guilherme Maurício (author), Chytry, Paola (author), Ferraz Dias, Johnny (author)Illegal trafficking of pharmaceutical products by criminal organisations is a global threat for public health. Drugs for erectile dysfunction such as phosphodiesterase type 5 inhibitors are the most commonly counterfeited medicines in Europe. The search of possible toxic chemical substances in seized products is needed to provide early...journal article 2020
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Kooijman, G. (author), de Kreuk, M.K. (author), Houtman, C. (author), van Lier, J.B. (author)Literature frequently reports that colloids in aqueous matrices sorb a large fraction of pharmaceuticals. Since coagulation/flocculation removes colloids, it is expected that coagulation/flocculation in principle should be useful in concentrating pharmaceuticals in wastewater treatment, which would facilitate the treatment of these refractory...journal article 2020
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Shah, Maulik (author)This thesis report is aimed at analysing two phenomena, the first being - the major trends which are shaping the pharmaceutical industry currently. The industry is witnessing massive strategic shifts, routine upgrades to new drug technologies in a dynamic regulatory and market environment. The growth rate of the global pharmaceutical industry is...master thesis 2019
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Zubin, Irene (author)The term last-mile delivery refers to the final leg of a business-to-customer service, in which a product is shipped from a depot to a final destination point by means of land transportation, such as vans and small trucks. Although they provide a common and easy way to consign products, companies are striving for new transport technologies to...master thesis 2019