Real-time oncological guidance using diffuse reflectance spectroscopy in electrosurgery: The effect of coagulation on tissue discrimination

In breast surgery, a lack of knowledge about what is below the tissue surface may lead to positive tumor margins and iatrogenic damage. Diffuse reflectance spectroscopy (DRS) is a spectroscopic technique that can distinguish between healthy and tumor tissue making it a suitable technology for intraoperative guidance. However, because tumor...

Diffuse Reflectance Spectroscopy for Intraoperative Tumor Margin Assessment: Workflow Analysis and Effect of Coagulation on Tissue Sensing

The aim of this graduation project is to assess the feasibility of the photonic technology called diffuse reflectance spectroscopy (DRS) to aid in intraoperative margin assessment with the goal of obtaining clear margins for liver, breast and soft tissue tumors. The idea is to integrate optical fibers in the existing and widely used...