Improving an optical diagnostics device for Schistosomiasis

Schistosomiasis is a Neglected Tropical Disease, prevailing mostly in poor and rural communities in sub-Saharan Africa, particularly those that heavily rely on water bound occupations, such as fishing and specific agriculture. In 2019, a total of 236.6 million people required treatment for schistosomiasis and only 1 million received it. Without...

An Upgrade for the Kato Katz Method

The kato katz method was, and still is, an invaluable tool to diagnose schistosomiasis mansoni en masse in high and medium intensity infection areas that are economically backward. Due to the current sensitivity capabilities of 24 EPG, the standard kato katz method is unable to diagnose very low intensity infections. And even though alternatives...

Towards a single shot holographic diagnosis of Schistosomiasis haematobium

Large scale, highly sensitive and specific diagnostic tools are needed to eliminate the transmission of schistosomiasis. This report expands upon the novel approach from M. Hoeboer and P.M. Nijman. Their Smart Optical Diagnostic Of Schistosomiasis device (SODOS), combining the principles of flow cytometry and digital holography, was able to...

The Smart Optical Diagnostic of Schistosomiasis

Urinary schistosomiasis is with over 110 million infected people one of the most common parasitic infections worldwide, most commonly found in Sub-Saharan Africa. Urinary schistosomiasis is caused by the Schistosoma Haematobium (SH) parasite. The most common diagnostic method is manual microscopy, in which urine is manually examined to see...

The EC: a device to diagnose urinary schistosomiasis in Ghana: Designed for local facilities as well as large-scale community screening sessions

This report is the result of a graduation project about Schistosomiasis, a neglected tropical disease caused by the Schistosoma parasite. And about a new technology to detect the parasitic infections. More specifically, to detect the urinary Schistosoma type, called S. haematobium.<br/><br/>Within Africa, a large number of countries are affected...

Smart Diagnostics for Low Resource Settings: Target product profiles for devices to diagnose urinary schistosomiasis in Nigeria

Urinary schistosomiasis is a neglected tropical disease caused by the Schistosoma haematobium parasite. People can get infected when they get into contact with contaminated fresh water. The disease is most prevalent amongst children, farmers and rural communities in Sub-Saharan Africa. Currently, the disease is diagnosed by microscopic egg count...

Parasite Detection using Hyperspectral Microscopy: Hyperspectral microscopy in Malaria and Schistosoma diagnostics: the approximation and detection of spectral signatures

Parasitic diseases such as malaria remain a mayor burden on global health. One of the biggest challenges still to be overcome is that of inadequate diagnoses. This research explores the opportunities that Hyperspectral Imaging yields in this field. The first goal is to estimate the spectral signature of Malaria parasites in non-stained or Giemsa...

Accelerating the development of UCP-LF CAA strip readers for schistosomiasis diagnosis

This document reports the exploration of the development of a context-specific strip reader for an innovative lateral flow test detecting schistosomiasis. Schistosomiasis is a common poverty-related parasitic disease in many Sub-Saharan African countries. Transmission happens in infested water, putting especially children at risk....

Explore the untapped digital data of neglected tropical disease, and provide insights for stakeholders to take strategic actions

People have been using the digital technology domain to seek solutions to combat neglected tropical diseases. Aside from feasibility and effectiveness, WHO has pointed out the importance of having an overview that pinpoints the lacking infrastructure for scaling up and sustaining digital proposals. This research demystifies the untapped digital...

Automating the Diagnosis and Quantification of Urinary Schistosomiasis

Schistosomiasis is a neglected tropical disease (NTD) that affects around a quarter-billion people worldwide. Most of the infected people live in tropical regions, especially in sub-Saharan Africa, where there is limited access to diagnostic and other relevant medical facilities. The current reference standard diagnostic procedure - conventional...

Stakeholder perspective on the context of use and application of a new diagnostic device for the diagnosis of schistosomiasis haematobium in Ibadan- Nigeria: Q-Methodoogy

Schistosomiasis is a Neglected Tropical Disease (NTD) that is caused by water-base parasite, putting more than 800 million people at risk. Sub-Saharan Africa accounts for approximately 93% of the world’s schistosomiasis cases with the highest prevalence is found in countries like Nigeria. Current diagnostic devices for schistosomiasis...

Digital holography integrated with flow cytometry for detection of urinary schistosomiasis

Schistosomiasis is an intravascular infection with major public health consequences in developing countries. It is one of the major Neglected Tropical Diseases with more than 240 million people infected and 800 million people at risk in 2015, mostly in sub-Saharan Africa. It is caused by trematode parasites of the genus Schistosoma, in this...