The integration of bulk PZT transducers in a microfabricated cuff implant for Vagus Nerve ultrasound neuromodulation: Simulation, design and fabrication

In the emerging research field of bioelectronic medicine, it has been indicated that neuromodulation of the Vagus Nerve (VN) has the potential to treat various conditions such as epilepsy, depression, and autoimmune diseases. In order to reduce side effects, as well as to increase the effectiveness of the delivered therapy, sub-fascicle...

Energy Efficient High Voltage Driver for High Frequency Ultrasound Medical Applications

Noninvasive brain stimulation plays an essential role in diagnosing and treating diseases of the brain. This stimulation can affect disease-related changes in brain activation, inhibition, or connectivity. Ultrasound neuromodulation is a rapidly growing field of noninvasive brain stimulation. In a form of acoustic pressure waves, ultrasound can...

Maximization of Transmitted Acoustic Intensity from Silicon Integrated Piezoelectric Ultrasound Transducers

2D phased array ultrasonic transducers realized through the combination of bulk piezoelectric ceramics and complementary metal-oxide-semiconductor (CMOS) integrated circuits (IC) are enabling a new range of wearable ultrasound therapeutic applications. Traditional therapeutic ultrasound transducers have an air backing layer to maximize...

An Integrated 2D Ultrasound Phased Array Transmitter in CMOS with Pixel Pitch-Matched Beamforming

Emerging non-imaging ultrasound applications, such as ultrasonic wireless power delivery to implantable devices and ultrasound neuromodulation, require wearable form factors, millisecond-range pulse durations and focal spot diameters approaching 100 μm with electronic control of its three-dimensional location. None of these are compatible...