Application of OCT and IVUS to investigate the combined effect of plaque structural stress and wall shear stress on plaque progression in human coronary arteries

Introduction: Atherosclerosis, the major source of cardiovascular diseases, is one of the leading causes of death. During atherosclerosis the arterial wall is affected by a complex process of lipid driven inflammation that leads to thickening of the arterial wall resulting in a so called plaque. Because of plaque growth, the lumen of the artery...