Trans-catheter aortic valve replacement (TAVR) has been widely used for treating Aortic stenosis (AoS). Numerical simulation of TAVR process is valuable in terms of reducing surgical risk for patients and cost for valve design. Finite element simulations are performed in this thesis to investigate the risk of coronary obstruction for patients who went through Aortic Valve Neo-cuspitization (AVNeo or Ozaki) procedure. The Expected Leaflet-to-ostium Distance was used as a criterion for assessing coronary obstruction risk. This value in 3 different deployment configurations is compared to determine the optimal deployment strategy. It is found that there is a large risk of coronary obstruction after TAVR for such patients under distal and midplane configuration but no risk under proximal configuration.