The research objective is to investigate the variations of sediment transport in outer Changjiang Estuary and adjacent Hangzhou Bay, induced by the decline of Changjiang River sediment discharge and massive land reclamation in the last three decades. A synchronous hydrographic survey was conducted along two transects (at the bay-mouth and outer Changjiang Estuary, respectively) during the spring-neap tides of January and July 2014. The results show that the suspended sediment grain size, current velocity, suspended sediment concentration (SSC), and the water and sediment fluxes varied with the tidal cycles. Quantitative correlations with the tidal range were found for SSC and fluxes. These data have been compared with those at the same hydrographic stations in the summer and winter of the early 1980s. Along the outer Changjiang Estuary transect, the SSCs and sediment fluxes decreased in the winter, but no apparent changes occurred in the summer. The SSCs in the northern Hangzhou Bay decreased in both summer and winter, while the southern bay mouth has evolved from a low SSC region to a high SSC region. The findings clarify that the SSC and sediment flux changes in this area have only an indirect connection to the dramatic riverine sediment decline, because the sediment resuspension by the strong tidal currents provided a major source. At the present stage, the impact of the riverine sediment decline is insignificant for the SSC variation off the Changjiang River mouth. Finally, a sediment flux model is proposed to explain and predict the morphological evolution trends.

Purpose
A novel three-dimensional (3D) T1 and T2 mapping protocol for the carotid artery is presented.

Methods
A 3D black-blood imaging sequence was adapted allowing carotid T1 and T2 mapping using multiple flip angles and echo time (TE) preparation times. B1 mapping was performed to correct for spatially varying deviations from the nominal flip angle. The protocol was optimized using simulations and phantom experiments. In vivo scans were performed on six healthy volunteers in two sessions, and in a patient with advanced atherosclerosis. Compensation for patient motion was achieved by 3D registration of the inter/intrasession scans. Subsequently, T1 and T2 maps were obtained by maximum likelihood estimation.

Results
Simulations and phantom experiments showed that the bias in T1 and T2 estimation was < 10% within the range of physiological values. In vivo T1 and T2 values for carotid vessel wall were 844 ± 96 and 39 ± 5 ms, with good repeatability across scans. Patient data revealed altered T1 and T2 values in regions of atherosclerotic plaque.

Conclusion
The 3D T1 and T2 mapping of the carotid artery is feasible using variable flip angle and variable TE preparation acquisitions. We foresee application of this technique for plaque characterization and monitoring plaque progression in atherosclerotic patients. Magn Reson Med 75:1008–1017, 2016.