The typical drivers of drought events are lower than normal precipitation and/or higher than normal evaporation. The region's characteristics may enhance or alleviate the severity of these events. Evaluating the combined effect of the multiple factors influencing droughts requires innovative approaches. This study applies hydrological modelling and a machine learning tool to assess the relationship between hydroclimatic characteristics and the severity of agricultural and hydrological droughts. The Soil Water Assessment Tool (SWAT) is used for hydrological modelling. Model outputs, soil moisture and streamflow, are used to calculate two drought indices, namely the Soil Moisture Deficit Index and the Standardized Streamflow Index. Then, drought indices are utilised to identify the agricultural and hydrological drought events during the analysis period, and the index categories are employed to describe their severity. Finally, the multivariate regression tree technique is applied to assess the relationship between hydroclimatic characteristics and the severity of agricultural and hydrological droughts. Our research indicates that multiple parameters influence the severity of agricultural and hydrological droughts in the Cesar River basin. The upper part of the river valley is very susceptible to agricultural and hydrological drought. Precipitation shortfalls and high potential evapotranspiration drive severe agricultural drought, whereas limited precipitation influences severe hydrological drought. In the middle part of the river, inadequate rainfall partitioning and an unbalanced water cycle that favours water loss through evapotranspiration and limits percolation cause severe agricultural and hydrological drought conditions. Finally, droughts are moderate in the basin's southern part (Zapatosa marsh and the Serranía del Perijá foothills). Moderate sensitivity to agricultural and hydrological droughts is related to the capacity of the subbasins to retain water, which lowers evapotranspiration losses and promotes percolation. Results show that the presented methodology, combining hydrological modelling and a machine learning tool, provides valuable information about the interplay between the hydroclimatic factors that influence drought severity in the Cesar River basin.@en