Wildfires are widely viewed as key evolving inputs of Mediterranean ecosystem. But anthropogenic climate changes and other socioecological recessions have transformed normal wildfire into megafire. The paradigm shift is needed since the suppression capacity has been increasingly overcome from the fire department. This research is aiming to integrate diverse landscape dynamics and fire regimes, to interpret the interactions between them and identify a series of heterogeneous fire typologies in the Mediterranean region in order to support the application of landscape-based approaches. By classifying the land system dynamics into meteorologic, physiographic, biological and anthropogenic indicators (in relation with wildfire ignition and propagation), geographic information system based approaches and statistic analysis are applied to create diagnostic mappings. The results establish 10 types of landscape-based fire typologies which can be used as the decision support tool to prioritize risk mechanism and then lead to mitigate wildfire risk by changing contextual territorial elements in landscape system in order to create an integral long time territorial design.