Av
Aafke van den Berg
Authored
5 records found
The interplay between polymerase organization and nucleosome occupancy along DNA
How dynamic roadblocks on the DNA induce the formation of RNA polymerase pelotons
During transcription RNA polymerase (RNAP) moves along a DNA molecule to copy the information on the DNA to an RNA molecule. Many textbook pictures show an RNAP sliding along empty DNA, but in reality it is crowded on the DNA and RNAP competes for space with many proteins such as
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During eukaryotic transcription, RNA polymerase (RNAP) translocates along DNA molecules covered with nucleosomes and other DNA binding proteins. Though the interactions between a single nucleosome and RNAP are by now fairly well understood, this understanding has not been synthes
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