We report in situ single-molecule measurements of proton-induced double-strand breaks (DSBs) in DNA immersed in water, using real-time fluorescence tracking along the entire proton path, including the Bragg peak region. By chemically suppressing radical-mediated processes, we isolate direct DNA damage mechanisms and determine DSB cross sections as a function of depth. Near the Bragg peak, we observe a tenfold reduction in DSB cross sections in aqueous DNA compared to dry DNA, providing quantitative evidence for the protective role of water. These findings highlight the importance of intermolecular energy dissipation in mitigating radiationinduced damage in condensed biological matter, with implications for radiobiology and proton therapy modeling. ... Read more

Infragravity (hereafter IG) waves are surface ocean waves with frequencies below those of wind-generated “short waves” (typically below 0.04 Hz). Here we focus on the most common type of IG waves, those induced by the presence of groups in incident short waves. Three related mechanisms explain their generation: (1) the development, shoaling and release of waves bound to the short-wave group envelopes (2) the modulation by these envelopes of the location where short waves break, and (3) the merging of bores (breaking wave front, resembling to a hydraulic jump) inside the surfzone. When reaching shallow water (O(1–10 m)), IG waves can transfer part of their energy back to higher frequencies, a process which is highly dependent on beach slope. On gently sloping beaches, IG waves can dissipate a substantial amount of energy through depth-limited breaking. When the bottom is very rough, such as in coral reef environments, a substantial amount of energy can be dissipated through bottom friction. IG wave energy that is not dissipated is reflected seaward, predominantly for the lowest IG frequencies and on steep bottom slopes. This reflection of the lowest IG frequencies can result in the development of standing (also known as stationary) waves. Reflected IG waves can be refractively trapped so that quasi-periodic along-shore patterns, also referred to as edge waves, can develop. IG waves have a large range of implications in the hydro-sedimentary dynamics of coastal zones. For example, they can modulate current velocities in rip channels and strongly influence cross-shore and longshore mixing. On sandy beaches, IG waves can strongly impact the water table and associated groundwater flows. On gently sloping beaches and especially under storm conditions, IG waves can dominate cross-shore sediment transport, generally promoting offshore transport inside the surfzone. Under storm conditions, IG waves can also induce overwash and eventually promote dune erosion and barrier breaching. In tidal inlets, IG waves can propagate into the back-barrier lagoon during the flood phase and induce large modulations of currents and sediment transport. Their effect appears to be smaller during the ebb phase, due to blocking by countercurrents, particularly in shallow systems. On coral and rocky reefs, IG waves can dominate over short-waves and control the hydro-sedimentary dynamics over the reef flat and in the lagoon. In harbors and semi-enclosed basins, free IG waves can be amplified by resonance and induce large seiches (resonant oscillations). Lastly, free IG waves that are generated in the nearshore can cross oceans and they can also explain the development of the Earth's “hum” (background free oscillations of the solid earth). ... Read more