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Malic Acid Production by Saccharomyces cerevisiae
Engineering of Pyruvate Carboxylation, Oxaloacetate Reduction, and Malate Export
Malic acid is a potential biomass-derivable "building block" for chemical synthesis. Since wild-type Saccharomyces cerevisiae strains produce only low levels of malate, metabolic engineering is required to achieve efficient malate production with this yeast. A promising pathway f
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