The sustainable solution of a prefabricated façade system with timber frame panels was the issue of this thesis. The choice of materials was one of the tasks. The use of loam and ceramics in the façade panels were examined as an improvement of the indoor climate while minimizing the energy consumption for the system demands. The application of the materials in a façade system in the Dutch climate led to the study of the thermo active building systems (TABS) in the inner layer. The comparison with standard systems and tests of the model by hand calculations and computational tools - CAPSOL gave a better view of the performance of the system and suggestions for improvements. Prefabrication was analyzed at the case study of the Concept House with suggestions for the design of the components and ways of attaching the panel to the construction.