The estimation of many-qubit observables is an essential task of quantum information processing. The generally applicable approach is to decompose the observables into weighted sums of multiqubit Pauli strings, i.e., tensor products of single-qubit Pauli matrices, which can readily be measured with low-depth Clifford circuits. The accumulation of shot noise in this approach, however, severely limits the achievable variance for a finite number of measurements. We introduce a novel method, dubbed coherent Pauli summation (CPS), that circumvents this limitation by exploiting access to a single-qubit quantum memory in which measurement information can be stored and accumulated. CPS offers a reduction in the required number of measurements for a given variance that scales linearly with the number of Pauli strings in the decomposed observable. Our work demonstrates how a single long-coherence qubit memory can assist the operation of many-qubit quantum devices in a cardinal task.