Brazil’s industrial emissions are 180 million tons of CO2 per year, and approximately 60% of these emissions are coming from industrial clusters located in the southeast. Tthe development of new offshore storage locations in this region is hence of strategic importance for future Carbon Capture and Storage (CCS) projects in Brazil. This study presents an evaluation of CO2 storage in the deep saline aquifers of the Jureia-Ponta Aguda formation, a gigaton-scale storage resource located in the shallow waters of Santos Basin that has the potential to support the development of at least three larger CCS hubs, each with a target injection of 1Gt of CO2. We show how Lorenz Coefficient map allows us to screen the pressure influence areas for each hub by linking reservoir heterogeneity to the spatio-temporal evolution of the pressure front, thereby identifying potential risks of pressure interference between neighboring CCS hubs.