Recent studies show an increase in energy use on buildings due to higher cooling demands, constituting an increase of 17% of the global energy consumption by 2050. Tendencies also show that cooling degree days around the globe will also increase and this will display a greater impact on developing countries with warm climates. Subsequently, this gives interest in reducing energy demands on buildings through both innovative passive and active design strategies that can convert these buildings into energy efficient buildings whilst reaching their desired comfort values. The potential to integrate these strategies for cooling system into a building façade has been looked into by recent research. As is the case of the thermoelectric technology, which is a promising cooling technology that has gained interest from architects in the past few years, and it has a great potential for integration. This device has the advantage of generating a temperature difference between the device’s two sides when direct current is applied it and so it has been widely studied and used as coolers at small scale. There are not enough studies and experimentation of integration at façade level has been conducted with this technology, and those that exists show that the system’s performance is still much lower than traditional air-conditioning systems. Thus, this graduation project focuses on a performance-based design, where the heat dissipation system’s design and its integration with the TE is explored and investigated, what parameters affects its performance, and, subsequently, their effect on the façade and the architecture of the building within a hot-arid climate in Mexico. For this, a combination of experiments and simulations were used to determine the effect certain design parameters have on the thermal performance of the heat dissipation system. Parallel to this, an office case study was selected, and simulations performed to determine the ideal passive strategies for reduction cooling load in a hot-arid climate. A stepped methodology was used for the experiments and simulations for the heat dissipation system and a comparative evaluation on different passive design strategies for the office design was applied. A simplified heat transfer model for the heat dissipation of the thermoelectrical technology was developed, where a series of design strategies were possible to be tested. Analysing the results determined which parameters had a greater impact on the design, for the heat dissipation system its performance was evaluated through its COP, and for the office design lower cooling loads were the defining parameter. General trends were identified on both evaluated levels and each show their potential. These were then translated into design guidelines for the heat dissipation system and office building design and then visualized as a final thermoelectrical facade design. The final COP of the cooling system based on the heat dissipation designed was 1.40. An evaluation on the designed TE façade was done, its limitations and potentials stated, as well as future possibilities that be further developed with this technology.