We derive a Z4 topological invariant that extends beyond symmetry eigenvalues and Wilson loops and classifies two-dimensional insulators with a C4T symmetry. To formulate this invariant, we consider an irreducible Brillouin zone and constrain the spectrum of the open Wilson lines that compose its boundary. We fix the gauge ambiguity of the Wilson lines by using the Pfaffian at high symmetry momenta. As a result, we distinguish the four C4T-protected atomic insulators, each of which is adiabatically connected to a different atomic limit. We establish the correspondence between the invariant and the obstructed phases by constructing both the atomic limit Hamiltonians and a C4T-symmetric model that interpolates between them. The phase diagram shows that C4T insulators allow ±1 and 2 changes of the invariant, where the latter is overlooked by symmetry indicators.

Breaking the dilemma between small size and room-temperature stability is a necessary prerequisite for skyrmion-based information technology. Here we demonstrate by means of rate theory and an atomistic spin Hamiltonian that the stability of isolated skyrmions in ultrathin ferromagnetic films can be enhanced by the concerted variation of magnetic interactions while keeping the skyrmion size unchanged. We predict film systems where the lifetime of sub-10 nm skyrmions can reach years at ambient conditions. The long lifetime of such small skyrmions is due to exceptionally large Arrhenius pre-exponential factor and the stabilizing effect of the energy barrier is insignificant at room temperature. A dramatic increase in the pre-exponential factor is achieved thanks to the softening of magnon modes of the skyrmion, thereby increasing the entropy of the skyrmion with respect to the transition state for collapse. Increasing the number of skyrmion deformation modes should be a guiding principle for the realization of nanoscale, room-temperature stable skyrmions.