In repetitive work, more physical variation is believed to reduce the risk of eventually developing musculoskeletal disorders. We investigated the extent to which workstation designs leading to more variation in upper arm postures during a pick-and-place task influenced outcomes of relevance to musculoskeletal disorder risk, including muscle activity, cardiovascular response, and perceived exertion, measured through the maximal acceptable work pace. Posture variation to the extent obtained in our experiment had only minor effects on these outcomes, and considerably less impact than a moderate change in working height. Apparently, substantial manipulations of the workstation or of the work task will be needed to accomplish variation to an extent that can significantly change outcomes of relevance to occupational musculoskeletal disorders and, thus, represent a potential for reduction in musculoskeletal disorder risk.@en