Carbon fiber reinforced polymer (CFRP) has emerged as an effective material for strengthening reinforced concrete (RC) structures due to its high tensile strength, corrosion resistance, and ease of installation. However, in square or rectangular RC columns, stress concentrations at corners hinder the development of uniform confinement, thereby reducing strengthening efficiency. This study presents a comprehensive experimental and theoretical investigation into the performance of CFRP-confined RC square columns with varying anchor configurations. Six full-scale column specimens were tested under monotonic axial compression, each externally wrapped with one layer of CFRP sheet and installed with zero to four CFRP anchors. All columns were chamfered with a 30 mm radius to mitigate corner stress concentrations. The experimental results demonstrated that CFRP anchors significantly enhanced load-bearing capacity and ductility, improved lateral confinement, and modified the failure mechanisms. The specimen with three anchors exhibited optimal performance, with a 51.5 % increase in peak load (from 879.9 kN to 1333.2 kN) and a 29.9 % improvement in ductility index compared to the unconfined control. The failure mode transitioned from brittle global instability to ductile localized damage, accompanied by more uniform hoop strain distribution. However, excessive anchoring introduced stress interference and local cracking, leading to performance degradation. To characterize the mechanical response, a modified stress–strain model was developed, incorporating a reduction factor to account for confinement weakening caused by anchor installation. The model exhibited strong agreement with experimental data (R² > 87 %) in predicting both peak and ultimate stresses. This study provides valuable insights into the mechanical enhancement mechanisms of CFRP anchoring systems and offers a rational design basis for strengthening non-circular RC columns in structural rehabilitation.