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Accurate determination of benzoic acid diffusion kinetics in s. cerevisiae using the Bioscope

Abstract - MTAP Kresnowati, WA van Winden, W.M. van Gulik, A. ten Pierick, JL Vinke, J.J. Heijnen

Changes in the metabolome of Saccharomyces cerevisiae associated with evolution in aerobic glucose-limited chemostats

Journal article - MR Mashego, MLA Jansen, JL Vinke, W.M. van Gulik, J.J. Heijnen

An improved bioscope design: a system for continuous pulse experiments

Poster - MR Mashego, JR Corcoi, JL Vinke, W.M. van Gulik, J.J. Heijnen

Application of metabolic flux analysis for the identification of metabolic bottlenecks in the biosynthesis of penicillin-G.

Journal article - W.M. van Gulik, WTAM de Laat, JL Vinke, J.J. Heijnen

Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards

Journal article - L Wu, MR Mashego, J.C. van Dam, A. ten Pierick, JL Vinke, C. Ras, WA van Winden, W.M. van Gulik, J.J. Heijnen

Metabolome analysis by isotope dilution mass spectrometry using fully-labeled cell extracts as internal standards

Poster - L Wu, MR Mashego, J.C. van Dam, A. ten Pierick, JL Vinke, C. Ras, WA van Winden, W.M. van Gulik, J.J. Heijnen

Energetics of growth and penicillin production in a high-producing strain of penicillium chrysogenum.

Journal article - W.M. van Gulik, MR Antoniewicz, WTAM de Laat, JL Vinke, J.J. Heijnen

In vivo kinetics with rapid perturbation experiments in Saccharomyces cerevisiae using a second-generation BioScope

Journal article - MR Mashego, W.M. van Gulik, JL Vinke, D Visser, J.J. Heijnen

Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of C-13-labeled primary metabolites

Journal article - WA van Winden, J.C. van Dam, C. Ras, RJ Kleijn, JL Vinke, W.M. van Gulik, J.J. Heijnen

In vivo kinetics of primary metabolism in Saccharomyces cerevisiae studied through prolonged chemostat cultication

Journal article - L Wu, MR Mashego, A. ten Pierick, JL Vinke, C. Ras, J.C. van Dam, WA van Winden, W.M. van Gulik, J.J. Heijnen

Micracle: Mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites.

Journal article - MR Mashego, L Wu, J.C. van Dam, C. Ras, JL Vinke, WA van Winden, W.M. van Gulik, J.J. Heijnen

Critical evaluation of sampling techniques for residual glucose determination in carbon-limited chemostat culture of Saccharomyces cerevisiae

Journal article - MR Mashego, W.M. van Gulik, JL Vinke, J.J. Heijnen

Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation

Journal article - WA van Winden, W.M. van Gulik, D Schipper, Peter J.T. Verheijen, P Krabben, JL Vinke, J.J. Heijnen

Influence of temperature on growth and ajmalicine production by Catharantus roseus suspension cultures

Journal article - HJG ten Hoopen, JL Vinke, PRH Moreno, R Verpoorte, J.J. Heijnen

An improved Bioscope design: a system for continuous pulse experiments

Poster - MR Mashego, JL Vinke, W.M. van Gulik, J.J. Heijnen

Abrasion of suspended biofilm pellets in airlift reactors: Importance of shape, structure and particle concentration.

Journal article - A Gjaltema, JL Vinke, Mark C.M. van Loosdrecht, J.J. Heijnen

JL Vinke

Authored