Inertial Measurement Units (IMUs) enable portable, multibody motion capture in diverse environments beyond the laboratory, making them a desirable choice for diagnosing mobility disorders and supporting rehabilitation in clinical or home settings. However, challenges associated with IMU measurements, including magnetic distortions and errors due to integration drift, complicate their broader use for motion capture. In this work, we propose a tightly coupled motion-capture approach that directly integrates IMU measurements with multibody dynamic models via an iterated extended Kalman filter to simultaneously estimate the system’s kinematics and kinetics. By enforcing the complete multibody system dynamics and utilizing only accelerometer and gyroscope data, our method accurately estimates joint kinematics and kinetics. Our algorithm is designed to fuse different sensor data, such as optical motion-capture measurements and joint torque readings, to further enhance estimation accuracy. We validated our approach using highly accurate ground-truth data from a 3-degree-of-freedom pendulum and a 6-degree-of-freedom collaborative robot. We demonstrate a maximum root-mean-square difference of 3.75° in the pendulum’s computed joint angles with respect to the marker motion-capture inverse kinematics. For the robot, we observed a maximum joint angle root-mean-square difference of 3.24° with respect to the joint encoders, while the maximum joint angle root-mean-square difference of the optical motion-capture inverse kinematics with respect to the encoders was 1.16°. With regard to kinetic estimates, we report a maximum joint torque root-mean-square difference of 3.02 Nm in the pendulum with respect to the marker motion-capture inverse dynamics and 4.27 Nm in the robot relative to its joint torque sensors.

Inertial measurement units (IMUs) are a promising means to capture human motion, yet obtaining meaningful biomechanical quantities from IMU measurements remains non-trivial. This tutorial-style review focuses on kinematics and introduces four key aspects (inertial human motion capture objective, environmental conditions, subject & attributes, and motion characteristics) to determine how to translate biomechanical problems into adequate formulations for the fusion of inertial sensor measurements. We identify three fundamental challenges for kinematics estimation from IMUs: IMUs do not provide direct information about the joint angle, IMUs do not measure their own orientation, and real-world environments and dynamics compromise sensor reliability. Though there exist widely-used methods to overcome these challenges, they suffer from severe limitations in real-life applications, e.g., the need for sensor-to-segment calibration, and the fact that magnetic field disturbances degrade joint angle accuracy. The full potential for many use-cases hence remains untapped in terms of accuracy and reliability. We share insights into recently proposed methods, e.g., exploiting the human body's kinematic chain constraints, having the potential to overcome these limitations. We also present guiding questions related to the four key aspects and illustrate their use for navigating the methodological landscape for the use-case of lower-extremity joint angle estimation, for which we share open-access code and compare the traditional workflow with three alternatives. Our aim is to bridge the gap between the sensor fusion community developing methods for human motion capture and the biomechanics community in need of accurate, easy-to-use, and reliable methods to study human motion outside of the laboratory.