This paper presents an investigation into the suitability of the SANISAND-MS model for the three-dimensional finite-element (3D FE) simulation of cyclic monopile behaviour in sandy soils. In addition to previous work on the subject, the primary focus of this study is to further assess the model's capability to reproduce the accumulation of permanent deflection/tilt under cyclic lateral load histories. To this end, experimental data from the PISA field campaign are employed, particularly those emerged from the medium-scale cyclic tests conducted at the Dunkirk site in France. The methodology adopted herein involves calibrating the SANISAND-MS model's parameters to align with 3D FE simulation of a selected monotonic pile test reported by the PISA team using a bounding surface plasticity model partly similar to SANISAND-MS. Subsequently, the soil parameters governing SANISAND-MS’ ratcheting response are calibrated using only minimal information from published PISA field data. While representing the first attempt to simulate the reference data set using a fully ‘implicit’ 3D FE approach, this paper offers novel insights into calibrating and using advanced cyclic models for monopile analysis and design – particularly, with regard to the quantitative influence of pile installation effects and sand's microstructural evolution under drained cyclic loading.