LW

Lin Wang

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4 records found

Journal article (2023) - Paul Corbae, Samuel Ciocys, Dániel Varjas, Ellis Kennedy, Steven Zeltmann, Manel Molina-Ruiz, Sinéad M. Griffin, Chris Jozwiak, Lin Wang Wang, More authors...
Crystalline symmetries have played a central role in the identification and understanding of quantum materials. Here we investigate whether an amorphous analogue of a well known three-dimensional strong topological insulator has topological properties in the solid state. We show that amorphous Bi2Se3 thin films host a number of two-dimensional surface conduction channels. Our angle-resolved photoemission spectroscopy data are consistent with a dispersive two-dimensional surface state that crosses the bulk gap. Spin-resolved photoemission spectroscopy shows this state has an anti-symmetric spin texture, confirming the existence of spin-momentum locked surface states. We discuss these experimental results in light of theoretical photoemission spectra obtained with an amorphous topological insulator tight-binding model, contrasting it with alternative explanations. The discovery of spin-momentum locked surface states in amorphous materials opens a new avenue to characterize amorphous matter, and triggers the search for an overlooked subset of quantum materials outside of current classification schemes. ...
Journal article (2021) - Xujie Zhang, Ping Wu, Jiajun He, Yichao Liu, Lin Wang, Jinfeng Gao
Currently, the offshore wind turbine has become a hot research area in the wind energy industry. Among different offshore wind turbines, floating offshore wind turbine (FOWT) can harvest abundant wind energy in deepwater areas. However, the harsh working environment will dramatically increase the maintenance cost and downtime of FOWTs. Wind turbine fault diagnosis is being regarded as an indispensable system for maintenance issues. Owing to the complexity of FOWT, it imposes an enormous challenge for effective fault diagnosis. This paper develops a novel FOWT fault diagnosis method based on a stacked denoising autoencoder (SDAE). First, a sliding window technique is adopted for time-series data to preserve temporal information. Then, SDAE is employed to extract the features from high-dimensional data. Based on the extracted features from SDAE, a classifier using multilayer perceptrons (MLP) is developed to determine the health status of the FOWT. To verify the performance of the proposed method, a FOWT simulation benchmark based on the National Renewable Energy Laboratory (NREL) FAST simulator is employed. Results show the superior performance of the proposed method by comparison with other relevant methods. ...
Journal article (2021) - Roel J.T. Mocking, Jane C. Naviaux, Robert K. Naviaux, Kefeng Li, Lin Wang, Jonathan M. Monk, A. Taylor Bright, Caroline A. Figueroa, Aart H. Schene, Henricus G. Ruhé, Johanna Assies
Recurrent major depressive disorder (rMDD) is a relapsing-remitting disease with high morbidity and a 5-year risk of recurrence of up to 80%. This was a prospective pilot study to examine the potential diagnostic and prognostic value of targeted plasma metabolomics in the care of patients with rMDD in remission. We used an established LC-MS/MS platform to measure 399 metabolites in 68 subjects with rMDD (n = 45 females and 23 males) in antidepressant-free remission and 59 age- and sex-matched controls (n = 40 females and 19 males). Patients were then followed prospectively for 2.5 years. Metabolomics explained up to 43% of the phenotypic variance. The strongest biomarkers were gender specific. 80% of the metabolic predictors of recurrence in both males and females belonged to 6 pathways: (1) phospholipids, (2) sphingomyelins, (3) glycosphingolipids, (4) eicosanoids, (5) microbiome, and (6) purines. These changes traced to altered mitochondrial regulation of cellular redox, signaling, energy, and lipid metabolism. Metabolomics identified a chemical endophenotype that could be used to stratify rrMDD patients at greatest risk for recurrence with an accuracy over 0.90 (95%CI = 0.69–1.0). Power calculations suggest that a validation study of at least 198 females and 198 males (99 cases and 99 controls each) will be needed to confirm these results. Although a small study, these results are the first to show the potential utility of metabolomics in assisting with the important clinical challenge of prospectively identifying the patients at greatest risk of recurrence of a depressive episode and those who are at lower risk. ...

Application in Anaesthetics

Journal article (2019) - Xuerui Wang, Yuting Zhang, Freek Kapteijn, Xiaoyu Wang, Eduardo Andres-Garcia, Peng Du, Lorena Giordano, Lin Wang, Zhou Hong, Xuehong Gu, Sohail Murad
Xe is only produced by cryogenic distillation of air, and its availability is limited by the extremely low abundance. Therefore, Xe recovery after usage is the only way to guarantee sufficient supply and broad application. Herein we demonstrate DD3R zeolite as a benchmark membrane material for CO2/Xe separation. The CO2 permeance after an optimized membrane synthesis is one order magnitude higher than for conventional membranes and is less susceptible to water vapour. The overall membrane performance is dominated by diffusivity selectivity of CO2 over Xe in DD3R zeolite membranes, whereby rigidity of the zeolite structure plays a key role. For relevant anaesthetic composition (<5 % CO2) and condition (humid), CO2 permeance and CO2/Xe selectivity stabilized at 2.0×10−8 mol m−2 s−1 Pa−1 and 67, respectively, during long-term operation (>320 h). This endows DD3R zeolite membranes great potential for on-stream CO2 removal from the Xe-based closed-circuit anesthesia system. The large cost reduction of up to 4 orders of magnitude by membrane Xe-recycling (>99+%) allows the use of the precious Xe as anaesthetics gas a viable general option in surgery. ...