XZ
Xuan Zheng
Authored
5 records found
Cell Tracking for Organoids
Lessons From Developmental Biology
Organoids have emerged as powerful model systems to study organ development and regeneration at the cellular level. Recently developed microscopy techniques that track individual cells through space and time hold great promise to elucidate the organizational principles of organs
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OrganoidTracker
Efficient cell tracking using machine learning and manual error correction
Time-lapse microscopy is routinely used to follow cells within organoids, allowing direct study of division and differentiation patterns. There is an increasing interest in cell tracking in organoids, which makes it possible to study their growth and homeostasis at the singlecell
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Although the spatiotemporal structure of the genome is crucial to its biological function, many basic questions remain unanswered on the morphology and segregation of chromosomes. Here, we experimentally show in Escherichia coli that spatial confinement plays a dominant role in d
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Although the physical properties of chromosomes, including their morphology, mechanics, and dynamics are crucial for their biological function, many basic questions remain unresolved. Here we directly image the circular chromosome in live E. coli with a broadened cell shape. We f
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Throughout the lifetime of living systems, tissue homeostasis and renewal constantly take place to confront challenging conditions, both internally, such as cell aging, and externally, such as infections, so that health can be maintained. Such processes require a tight balance be
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