Background: Disruptions in freight transportation—such as service delays, infrastructure failures, and labor strikes—pose significant challenges to the reliability and efficiency of intermodal networks. To address these challenges, this study introduces Adaptive Intermodal Transportation (AIT), a resilient and flexible planning framework that enhances Synchromodal Freight Transport (SFT) by integrating real-time disruption management. Methods: Building on recent advances, we propose two novel strategies: (1) Reassign with Delay Buffer, which enables dynamic rerouting of shipments within a user-defined delay tolerance, and (2) (De)Consolidation, which allows splitting or merging of shipments across services depending on available capacity. These strategies are incorporated into a re-planning module that complements a baseline optimization model and a continuous disruption-monitoring system. Numerical experiments conducted on a Great Lakes-based case study evaluate the performance of the proposed strategies against a benchmark approach. Results: Results show that under moderate and high-disruption conditions, the proposed strategies reduce delay and disruption-incurred costs while increasing the percentage of matched shipments. The Reassign with Delay Buffer strategy offers controlled flexibility, while (De)Consolidation improves resource utilization in constrained environments. Conclusions: Overall, the AIT framework demonstrates strong potential for improving operational resilience in intermodal freight systems by enabling adaptive, disruption-aware planning decisions.