We construct n-consistent and asymptotically normal estimates for the finite dimensional regression parameter in the current status linear regression model, which do not require any smoothing device and are based on maximum likelihood estimates (MLEs) of the infinite dimensional parameter. We also construct estimates, again only based on these MLEs, which are arbitrarily close to efficient estimates, if the generalized Fisher information is finite. This type of efficiency is also derived under minimal conditions for estimates based on smooth nonmonotone plug-in estimates of the distribution function. Algorithms for computing the estimates and for selecting the bandwidth of the smooth estimates with a bootstrap method are provided. The connection with results in the econometric literature is also pointed out.

Single-index models are popular regression models that are more flexible than linear models and still maintain more structure than purely nonparametric models. We consider the problem of estimating the regression parameters under a monotonicity constraint on the unknown link function. In contrast to the standard approach of using smoothing techniques, we review different "non-smooth" estimators that avoid the difficult smoothing parameter selection. For about 30 years, one has had the conjecture that the profile least squares estimator is an n-consistent estimator of the regression parameter, but the only non-smooth argmin/argmax estimators that are actually known to achieve this n-rate are not based on the nonparametric least squares estimator of the link function. However, solving a score equation corresponding to the least squares approach results in n-consistent estimators. We illustrate the good behavior of the score approach via simulations. The connection with the binary choice and current status linear regression models is also discussed.

We discuss a new way of constructing pointwise confidence intervals for the distribution function in the current status model. The confidence intervals are based on the smoothed maximum likelihood estimator, using local smooth functional theory and normal limit distributions. Bootstrap methods for constructing these intervals are considered. Other methods to construct confidence intervals, using the non-standard limit distribution of the (restricted) maximum likelihood estimator, are compared with our approach via simulations and real data applications.

We consider estimation in the single-index model where the link function is monotone. For this model, a profile least-squares estimator has been proposed to estimate the unknown link function and index. Although it is natural to propose this procedure, it is still unknown whether it produces index estimates that converge at the parametric rate. We show that this holds if we solve a score equation corresponding to this least-squares problem. Using a Lagrangian formulation, we show how one can solve this score equation without any reparametrization. This makes it easy to solve the score equations in high dimensions. We also compare our method with the effective dimension reduction and the penalized least-squares estimator methods, both available on CRAN as R packages, and compare with link-free methods, where the covariates are elliptically symmetric.