Climate Resilient Development Pathways (CRDP) is a promising concept for cities to integrate climate change mitigation and adaptation to achieve sustainable development for all. Although CRDP aims to leverage synergies and co-benefits while limiting trade-offs between a city’s many objectives, there is no framework or approach for planning and implementing CRDP. A structured approach is needed to move from theory to practice. In this perspective paper, we outline three functional elements, or building blocks, for a CRDP planning framework. The building blocks are (1) identifying and evaluating interactions between adaptation, mitigation and sustainable development, (2) addressing time and uncertainty in planning, and (3) delivering specialized information for CRDP. These building blocks are informed by practice, drawing lessons from literature on recent efforts to integrate climate adaptation and mitigation in European cities, and from our experiences with adaptive pathways planning and climate services development. As cities and scholars are turning their attention to CRDP planning, the building blocks can help focus priority areas for development, informed by practice.