Plastic pollution is a global environmental challenge that negatively impacts species, ecosystems, and human livelihoods. River basins, with high population densities and poor waste management, are particularly exposed to plastic pollution. Floods amplify the presence of plastic in rivers by mobilizing previously deposited materials and introducing new plastics. Yet, the fate of these mobilized plastics remains unclear, with observations suggesting either downstream export or floodplain deposition. This study assesses flood impact on macroplastic deposition along river floodplains, using data from 14 events─five floods and nine nonflood conditions─across two Dutch rivers. Higher flood return periods increased macroplastic deposition, with the two largest floods depositing two to three times more macroplastic than nonflood conditions. Deposition mechanisms varied by flood type. Obstruction-based deposition dominated during an extreme summer flood, when macroplastics accumulated mainly in inundated vegetation. Low-energy deposition prevailed during a long winter flood, with high plastic concentrations found in wide floodplain sections where flow velocities decreased. Flood severity and plastic entry into the environment are both projected to increase. Therefore, we expect an even more prominent role for floods in the global distribution of plastic pollution.