Deep confocal fluorescence microscopy with single-photon superconducting nanowire detector
Fei Xia (Cornell University College of Engineering, Sorbonne Université)
Monique Gevers (Single Quantum)
Andreas Fognini (Single Quantum)
Aaron T. Mok (Cornell University College of Engineering)
Bo Li (Cornell University College of Engineering)
Najva Akabri (Cornell University College of Engineering)
Iman Esmaeil Zadeh (Single Quantum, TU Delft - ImPhys/Optics)
Jessie Qin-Dregely (Single Quantum)
Chris Xu (Cornell University College of Engineering)
More Info
expand_more
Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.
Abstract
Using short-wave infrared wavelength advantages, we demonstrate one-photon fluorescence confocal microscopy of adult mouse brains with penetration depths up to 1.7mm. This is achieved by labeling quantum dots with 1300 nm excitation and 1700 nm emission and detecting them with a single-photon superconducting nanowire detector.