Grand Research Challenges for Sustainable Industrial Biotechnology
Adrie Straathof (TU Delft - BT/Bioprocess Engineering)
SA Wahl (TU Delft - OLD BT/Cell Systems Engineering)
Kirsten R. Benjamin (Amyris Inc)
Ralf Takors (University of Stuttgart)
Nick Wierckx (Forschungszentrum Jülich)
H.J. Noorman (TU Delft - BT/Bioprocess Engineering, DSM)
More Info
expand_more
Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.
Abstract
Future manufacturing will focus on new, improved products as well as on new and enhanced production methods. Recent biotechnological and scientific advances, such as CRISPR/Cas and various omic technologies, pave the way to exciting novel biotechnological research, development, and commercialization of new sustainable products. Rigorous mathematical descriptions of microbial cells and consortia thereof will enable deeper biological understanding and lead to powerful in silico cellular models. Biological engineering, namely model-based design together with synthetic biology, will accelerate the construction of robust and high-performing microorganisms. Using these organisms, and ambitions towards zero-concepts with respect to emissions and excess resources in bioprocess engineering, industrial biotechnology is expected to become highly integrated into sustainable generations of technology systems.