Automated Benchmark Construction for Factual Question Answering over NHG Guidelines

A Foundation for RAG Evaluation in Dutch Primary Care

Bachelor Thesis (2026)
Author(s)

C.K. Bakker (TU Delft - Electrical Engineering, Mathematics and Computer Science)

Contributor(s)

Yannick ter Heerdt – Mentor (Erasmus MC)

J. Yang – Mentor (TU Delft - Electrical Engineering, Mathematics and Computer Science)

P.K. Murukannaiah – Graduation committee member (TU Delft - Electrical Engineering, Mathematics and Computer Science)

Faculty
Electrical Engineering, Mathematics and Computer Science
More Info
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Publication Year
2026
Language
English
Graduation Date
26-06-2026
Awarding Institution
Delft University of Technology
Project
CSE3000 Research Project
Programme
Computer Science and Engineering
Faculty
Electrical Engineering, Mathematics and Computer Science
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Abstract

Evaluating Retrieval-Augmented Generation systems in clinical domains requires
reliable benchmarks, yet constructing these manually is costly and infeasible at a large scale. This paper presents an automated pipeline for constructing and evaluating a factual question answering benchmark over Dutch primary care guidelines. The pipeline uses large language model based question-answer generation with few-shot and chain-of-thought prompting, combined with automated filtering using BERTScore grounding and round-trip consistency to produce high quality question-answer pairs. Human validation confirmed that the final benchmark of 192 question-answer pairs across 10 Nederlands Huisartsen Genootschap guidelines achieves factual correctness, retraceability and clinical relevance. The benchmark was integrated into a Retrieval-Augmented Generation pipeline to evaluate whether RAGChecker, a claim-level automated evaluation framework, could serve as a reliable alternative to human evaluation. RAGChecker
scores were consistent with human judgment though lower due to its strict claim-level checking. These results show that a reliable, automated benchmark can be constructed for Dutch primary care question answering and that RAGChecker serves as a reasonable but strict alternative for human evaluation of Retrieval-Augmented Generation systems in this domain.

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