Modeling of blood flow in aorta

MRI-based computational fluid dynamics of aortic hemodynamics

Doctoral thesis (2023)

Authors

R. Perinajová ChemE/Transport Phenomena - AS
Research Group
ChemE/Transport Phenomena (AS) (TU Delft)
Copyright: © 2023 R. Perinajová
DOI
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https://doi.org/10.4233/uuid:1cc9228c-514c-42ee-9edb-6d7596d66f11
Computational Fluid Dynamics Simulations 4D-flow MRI Aorta
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Published Date

2023

Language

English

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Faculty

Applied Sciences

Department

ChemE/Chemical Engineering

Research Group

ChemE/Transport Phenomena

Abstract

Aortic aneurysm, a balloon-like enlargement of the healthy artery, is a cardiovascular disease with one of the highest mortality rates. These numbers are due to the usual late diagnosis of the aneurysm, which is often asymptomatic until a fatal event occurs. Such an event can progress to aortic dissection or rupture. Due to the urgent nature of a rupture, we require early detection of asymptomatic aneurysms and proper evaluation of the rupture risk. The clinical guidelines suggest a close follow-up of the luminal size evolution, with advice for surgery based on threshold values. The thresholds are based on the annual maximum arterial diameter or growth rate. However, these guidelines are lacking in many cases.