The clinical utilities of multi-pinhole single photon emission computed tomography
Ilker Ozsahin (Near East University, Nicosia, University of Macau)
Ling Chen (University of Macau)
Arda Könik (Dana-Farber Cancer Institute, Boston)
Michael A. King (University of Massachusetts Medical School)
Freek J. Beekman (TU Delft - RST/Biomedical Imaging, MILabs B.V., University Medical Centre Utrecht)
Greta S.P. Mok (University of Macau)
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Abstract
Single photon emission computed tomography (SPECT) is an important imaging modality for various applications in nuclear medicine. The use of multi-pinhole (MPH) collimators can provide superior resolution-sensitivity trade-off when imaging small field-of-view compared to conventional parallel-hole and fan-beam collimators. Besides the very successful application in small animal imaging, there has been a resurgence of the use of MPH collimators for clinical cardiac and brain studies, as well as other small field-of-view applications. This article reviews the basic principles of MPH collimators and introduces currently available and proposed clinical MPH SPECT systems.
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