Spread-Spectrum Modulated Multi-Channel Biosignal Acquisition Using a Shared Analog CMOS Front-End

Journal article (2023)

Authors

Samprajani Rout Student
G.L.E. Monna Phosphoenix, Bio-Electronics - EEMCS
Fabio Pareschi Politecnico di Torino
Gianluca Setti King Abdullah University of Science and Technology
W.A. Serdijn Bio-Electronics - EEMCS
Research Group
Bio-Electronics (EEMCS) (TU Delft)
Copyright: © 2023 Samprajani Rout, G.L.E. Monna, Fabio Pareschi, Gianluca Setti, W.A. Serdijn
DOI
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https://doi.org/10.1109/TBCAS.2023.3317188
ECG Codes Iron Atrial electrograms Modulation Wires Recording Frequency modulation Biosignal acquisition Frequency division multiplexing Gold codes Linear- feedback shift register Multi-channel signal acquisition Sigma-delta converter Spread-spectrum modulation
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Published Date

2023

Language

English

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Faculty

Electrical Engineering, Mathematics and Computer Science

Department

Microelectronics

Research Group

Bio-Electronics

Abstract

The key challenges in designing a multi-channel biosignal acquisition system for an ambulatory or invasive medical application with a high channel count are reducing the power consumption, area consumption and the outgoing wire count. This article proposes a spread-spectrum modulated biosignal acquisition system using a shared amplifier and an analog-to-digital converter (ADC). We propose a design method to optimize a recording system for a given application based on the required SNR performance, number of inputs, and area. The proposed method is tested and validated on real pre-recorded atrial electrograms and achieves an average percentage root-mean-square difference (PRD) performance of 2.65% and 3.02% for sinus rhythm (SR) and atrial fibrillation (AF), respectively by using pseudo-random binary-sequence (PRBS) codes with a code-length of 511, for 16 inputs. We implement a 4-input spread-spectrum analog front-end in a 0.18 μ m CMOS process to demonstrate the proposed approach. The analog front-end consists of a shared amplifier, a 2nd order Σ Δ ADC sampled at 7.8 MHz, used for digitization, and an on-chip 7-bit PRBS generator. It achieves a number-of-inputs to outgoing-wire ratio of 4:1 while consuming 23 μ A/input including biasing from a 1.8 V power supply and 0.067 mm
2 in area.