Spread-Spectrum Modulated Multi-Channel Biosignal Acquisition Using a Shared Analog CMOS Front-End

Journal Article (2023)
Author(s)

Samprajani Rout (Student TU Delft)

G.L.E. Monna (Phosphoenix, TU Delft - Bio-Electronics)

Fabio Pareschi (Politecnico di Torino)

Gianluca Setti (King Abdullah University of Science and Technology)

W. A. Serdijn (TU Delft - Bio-Electronics)

Research Group
Bio-Electronics
Copyright
© 2023 Samprajani Rout, G.L.E. Monna, Fabio Pareschi, Gianluca Setti, W.A. Serdijn
DOI related publication
https://doi.org/10.1109/TBCAS.2023.3317188
More Info
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Publication Year
2023
Language
English
Copyright
© 2023 Samprajani Rout, G.L.E. Monna, Fabio Pareschi, Gianluca Setti, W.A. Serdijn
Research Group
Bio-Electronics
Issue number
4
Volume number
17
Pages (from-to)
872-884
Reuse Rights

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Abstract

The key challenges in designing a multi-channel biosignal acquisition system for an ambulatory or invasive medical application with a high channel count are reducing the power consumption, area consumption and the outgoing wire count. This article proposes a spread-spectrum modulated biosignal acquisition system using a shared amplifier and an analog-to-digital converter (ADC). We propose a design method to optimize a recording system for a given application based on the required SNR performance, number of inputs, and area. The proposed method is tested and validated on real pre-recorded atrial electrograms and achieves an average percentage root-mean-square difference (PRD) performance of 2.65% and 3.02% for sinus rhythm (SR) and atrial fibrillation (AF), respectively by using pseudo-random binary-sequence (PRBS) codes with a code-length of 511, for 16 inputs. We implement a 4-input spread-spectrum analog front-end in a 0.18 μ m CMOS process to demonstrate the proposed approach. The analog front-end consists of a shared amplifier, a 2nd order Σ Δ ADC sampled at 7.8 MHz, used for digitization, and an on-chip 7-bit PRBS generator. It achieves a number-of-inputs to outgoing-wire ratio of 4:1 while consuming 23 μ A/input including biasing from a 1.8 V power supply and 0.067 mm
2 in area.

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