Catheter design optimization for practical intravascular photoacoustic imaging (IVPA) of vulnerable plaques

Conference paper (2018)

Authors

Sophinese Iskander-Rizk Erasmus MC

Min Wu Erasmus MC

Geert Springeling Erasmus MC

Frits Mastik Erasmus MC

Robert Beurskens Erasmus MC

Antonius F.W. van der Steen Erasmus MC

Gijs Van Soest Erasmus MC

Affiliation

External organisation

Intravascular Photoacoustics IVPA catheter IVPA sheath Lipid-rich plaque imaging

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Published Date

2018

Language

English

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Affiliation

External organisation

Abstract

Intravascular photoacoustic/ultrasound imaging (IVPA/US) can image the structure and composition of atherosclerotic lesions identifying lipid-rich plaques ex vivo and in vivo. In the literature, multiple IVPA/US catheter designs were presented and validated both in ex-vivo models and preclinical in-vivo situations. Since the catheter is a critical component of the imaging system, we discuss here a catheter design oriented to imaging plaque in a realistic and translatable setting. We present a catheter optimized for light delivery, manageable flush parameters and robustness with reduced mechanical damage risks at the laser/catheter joint interface. We also show capability of imaging within sheath and in water medium.