Draft Genome Sequences of Two Extensively Drug-Resistant Strains of <em>Mycobacterium tuberculosis</em> Belonging to the Euro-American S Lineage

Journal article (2016)

Authors

Lesibana A. Malinga University of Pretoria, South African Medical Research Council
T.E.P.M.F. Abeel Pattern Recognition and Bioinformatics - EEMCS , Broad Institute of MIT and Harvard
CA Desjardins Broad Institute of MIT and Harvard
Talent C. Dlamini Southern Africa Nazarene University
Gail Cassell Harvard University
SB Chapman Broad Institute of MIT and Harvard
BW Birren Broad Institute of MIT and Harvard
AM Earl Broad Institute of MIT and Harvard
Martie van der Walt South African Medical Research Council
Research Group
Pattern Recognition and Bioinformatics (EEMCS) (TU Delft)
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Published Date

2016

Language

English

Faculty

Electrical Engineering, Mathematics and Computer Science

Department

Intelligent Systems

Research Group

Pattern Recognition and Bioinformatics

Abstract

We report the whole-genome sequencing of two extensively drug-resistant tuberculosis strains belonging to the Euro-American S lineage. The RSA 114 strain showed single-nucleotide polymorphisms predicted to have drug efflux activity.