Several Agent-Based and Cellular Automata Mathematical Frameworks for Modeling Pancreatic Cancer
Jiao Chen (TU Delft - Electrical Engineering, Mathematics and Computer Science, Amsterdam UMC)
Fred J. Vermolen (Universiteit Hasselt, TU Delft - Electrical Engineering, Mathematics and Computer Science)
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Abstract
Mathematical modeling sheds light on cancer research. In addition to reducing animal-based experiments, mathematical modeling is able to provide predictions and prevalidate hypotheses quantitatively. In this work, two different agent-based frameworks regarding cancer modeling are summarised. In contrast, cell-based models focus on the behavior of every single cell and presents the interaction of cells on a small scale, whereas, cellular automata models are used to simulate the interaction of cells with their microenvironment on a large tissue scale.