Projection-Wise Disentangling for Fair and Interpretable Representation Learning

Application to 3D Facial Shape Analysis

Conference Paper (2021)
Author(s)

Xianjing Liu (Erasmus MC)

Bo Li (Erasmus MC)

Esther E. Bron (Erasmus MC)

W. J. Niessen (Erasmus MC, TU Delft - ImPhys/Computational Imaging, TU Delft - ImPhys/Medical Imaging)

E. B. Wolvius (Erasmus MC)

Gennady V. Roshchupkin (Erasmus MC)

Research Group
ImPhys/Medical Imaging
DOI related publication
https://doi.org/10.1007/978-3-030-87240-3_78
More Info
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Publication Year
2021
Language
English
Research Group
ImPhys/Medical Imaging
Pages (from-to)
814-823
ISBN (print)
9783030872397

Abstract

Confounding bias is a crucial problem when applying machine learning to practice, especially in clinical practice. We consider the problem of learning representations independent to multiple biases. In literature, this is mostly solved by purging the bias information from learned representations. We however expect this strategy to harm the diversity of information in the representation, and thus limiting its prospective usage (e.g., interpretation). Therefore, we propose to mitigate the bias while keeping almost all information in the latent representations, which enables us to observe and interpret them as well. To achieve this, we project latent features onto a learned vector direction, and enforce the independence between biases and projected features rather than all learned features. To interpret the mapping between projected features and input data, we propose projection-wise disentangling: a sampling and reconstruction along the learned vector direction. The proposed method was evaluated on the analysis of 3D facial shape and patient characteristics (N = 5011). Experiments showed that this conceptually simple method achieved state-of-the-art fair prediction performance and interpretability, showing its great potential for clinical applications.

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