Combating food health misinformation and disinformation with advanced RAG-LLM
Prototype AI on PubMed for cardiac health
L.P.A. Simons (TU Delft - Electrical Engineering, Mathematics and Computer Science)
P.K. Murukannaiah (TU Delft - Electrical Engineering, Mathematics and Computer Science)
M.A. Neerincx (TU Delft - Electrical Engineering, Mathematics and Computer Science)
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Abstract
Effective prevention and treatment of cardiovascular disease rely on healthy lifestyle behaviors. However, the expanding and often conflicting nature of scientific literature, along with prevalent food and health misinformation/disinformation, hinders informed decision-making. Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG) capabilities offer automated claim verification and summarization. An enhanced RAG-LLM prototype with novel modules is evaluated for effectiveness. Results show that Inclusion-Criteria-based filtering of PubMed articles improved verdict accuracy. Furthermore, employing a PICO-based (Population, Intervention, Comparison, Outcome) approach for summarizing evidence in health claims (e.g., 'Berries reduce blood pressure') increased transparency. Still, the tested RAG-LLM models exhibited biases towards positivity (overemphasizing heart-healthy aspects) and neutrality. Likely causes of these biases and future development challenges are discussed, as well as AI tooling enabling governance on industry influences in nutrition science.
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File under embargo until 04-01-2027