Properties of Maxentropic DNA Synthesis Codes †

Journal Article (2024)
Author(s)

Kees A. Immink (Turing Machines Inc.)

Jos Weber (TU Delft - Discrete Mathematics and Optimization)

Kui Cai (Singapore University of Technology and Design)

Research Group
Discrete Mathematics and Optimization
DOI related publication
https://doi.org/10.3390/e26121028
More Info
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Publication Year
2024
Language
English
Research Group
Discrete Mathematics and Optimization
Issue number
12
Volume number
26
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Abstract

Low-weight codes have been proposed for efficiently synthesizing deoxyribonucleic acid (DNA) for massive data storage, where a multiple of DNA strands are synthesized in parallel. We report on the redundancy and information rate of maxentropic low-weight codes for asymptotically large codeword length. We compare the performance of low-complexity nibble replacement (NR) codes, which are designed to minimize the synthesis time, with the performance of maxentropic low-weight codes. Finally, the asymptotic redundancy and information rate of codes with a runlength limitation are investigated.