Advancing Deep Hyperthermia: the design and realisation of a Microwave Tomography and Hyperthermia treatment system
M.J.A. Jansen (TU Delft - Mechanical Engineering)
K. W. A. van Dongen – Mentor (TU Delft - ImPhys/Medical Imaging)
Massimiliano Zanoli – Mentor (Erasmus MC)
Nazlı Tümer – Graduation committee member (TU Delft - Biomaterials & Tissue Biomechanics)
B Rieger – Graduation committee member (TU Delft - ImPhys/Computational Imaging)
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Abstract
This thesis is concerned with the technical, physical and computational challenges regarding
the incorporation of microwave tomography in hyperthermia treatments. Hyperthermia is a
clinical technique in which tumorous tissue is heated to gain therapeutic effect for concurrent
radiotherapy. Hyperthermia by microwaves, as performed at the Erasmus Medical Center,
suffers from uncertainties and lacking control. To relieve the burden of uncertainties regarding
dielectric properties and patient positioning, microwave tomography can be used in hyperthermia systems. This could also improve treatments, as it would offer more possibilities for
controlling the delivery. This work is focused on relieving several practical limitations to the
integration of tomography, rather than researching its possibilities. This thesis is accompanied by the literature research “Advancements in Microwave Tomography and Hyperthermia
Treatments” by the same author.