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Electrochemical Amplification in Side-by-Side Attoliter Nanogap Transducers

Journal Article (2017)
Author(s)

Hamid Zafarani (TU Delft - OLD ChemE/Organic Materials and Interfaces)

Klaus Mathwig (Rijksuniversiteit Groningen)

EJR Sudholter (TU Delft - OLD ChemE/Organic Materials and Interfaces)

Liza Rassaei (TU Delft - OLD ChemE/Organic Materials and Interfaces)

Research Group
OLD ChemE/Organic Materials and Interfaces
Copyright
© 2017 H. Zafarani, Klaus Mathwig, Ernst J. R. Sudhölter, L. Rassaei
DOI related publication
https://doi.org/10.1021/acssensors.7b00180
More Info
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Publication Year
2017
Language
English
Copyright
© 2017 H. Zafarani, Klaus Mathwig, Ernst J. R. Sudhölter, L. Rassaei
Research Group
OLD ChemE/Organic Materials and Interfaces
Issue number
6
Volume number
2
Pages (from-to)
724-728
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Abstract

We report a strategy for the fabrication of a new type of electrochemical nanogap transducer. These nanogap devices are based on signal amplification by redox cycling. Using two steps of electron-beam lithography, vertical gold electrodes are fabricated side by side at a 70 nm distance encompassing a 20 attoliter open nanogap volume. We demonstrate a current amplification factor of 2.5 as well as the possibility to detect the signal of only 60 analyte molecules occupying the detection volume. Experimental voltammetry results are compared to calculations from finite element analysis.