Photobiocatalytic alcohol oxidation using LED light sources
Marine C.R. Rauch (TU Delft - BT/Biocatalysis)
Sandy Schmidt (TU Delft - BT/Biocatalysis)
IWCE Arends (TU Delft - BT/Biotechnologie)
K. oppelt (Johannes Kepler University Linz)
S Kara (Hamburg University of Technology)
Frank Hollmann (TU Delft - BT/Biocatalysis)
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Abstract
The photocatalytic oxidation of NADH using a flavin photocatalyst and a simple blue LED light source is reported. This in situ NAD+ regeneration system can be used to promote biocatalytic, enantioselective oxidation reactions. Compared to the traditional use of white light bulbs this method enables very significant reductions in energy consumption and CO2 emission.