In vivo intravascular photoacoustic imaging of plaque lipid in coronary atherosclerosis

Journal article (2019)

Authors

Min Wu Eindhoven University of Technology
Geert Springeling Erasmus MC
Frits Mastik Erasmus MC
Robert Beurskens Erasmus MC
A.F.W. van der Steen ImPhys/Verweij group - AS , Erasmus MC
Gijs Van Soest Erasmus MC
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Research Group
ImPhys/Verweij group (AS) (TU Delft)
Optical coherence tomography Intravascular ultrasound Other imaging modalities
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Published Date

2019

Language

English

Reuse Rights

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Faculty

Applied Sciences

Department

ImPhys/Imaging Physics

Research Group

ImPhys/Verweij group

Abstract

Prospective identification of lipid-rich vulnerable plaque has remained an elusive goal. Intravascular photoacoustics, a hybrid optical and ultrasonic technology, was developed as a tool for lipid-rich plaque imaging. Here, we present the first in vivo images of lipid-rich coronary atherosclerosis acquired with this new technology in a large animal model, and relate them to independent catheter-based imaging and histology.