In vivo intravascular photoacoustic imaging of plaque lipid in coronary atherosclerosis
Sophinese Iskander-Rizk (Erasmus MC)
Min Wu (Eindhoven University of Technology)
G Springeling (Erasmus MC)
H. M.M. van Beusekom (Erasmus MC)
Frits Mastik (Erasmus MC)
Maaike Te Lintel te Lintel Hekkert (Erasmus MC)
R. H.S.H. Beurskens (Erasmus MC)
Antonius F.W. van der Steen (TU Delft - ImPhys/Verweij group, Erasmus MC)
Gijs Van Van Soest (Erasmus MC)
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Abstract
Prospective identification of lipid-rich vulnerable plaque has remained an elusive goal. Intravascular photoacoustics, a hybrid optical and ultrasonic technology, was developed as a tool for lipid-rich plaque imaging. Here, we present the first in vivo images of lipid-rich coronary atherosclerosis acquired with this new technology in a large animal model, and relate them to independent catheter-based imaging and histology.
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