Multi-agent systems for chemical engineering

a review and perspective

Review (2026)
Author(s)

Sophia Rupprecht (TU Delft - ChemE/Process Systems Engineering)

Qinghe Gao (TU Delft - ChemE/Process Systems Engineering)

Tanuj Karia (TU Delft - ChemE/Process Systems Engineering)

Artur M. Schweidtmann (TU Delft - ChemE/Process Systems Engineering)

Research Group
ChemE/Process Systems Engineering
DOI related publication
https://doi.org/10.1016/j.coche.2025.101209
More Info
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Publication Year
2026
Language
English
Research Group
ChemE/Process Systems Engineering
Volume number
51
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Abstract

Large language model (LLM)-based multi-agent systems (MASs) are a recent but rapidly evolving technology with the potential to transform chemical engineering by decomposing complex workflows into teams of collaborative agents with specialized knowledge and tools. This review surveys the state-of-the-art of MASs within chemical engineering. While early studies demonstrate promising results, scientific challenges remain, including the design of tailored architectures, integration of heterogeneous data modalities, development of foundation models with domain-specific modalities, and strategies for ensuring transparency, safety, and environmental impact. As a young but fast-moving field, MASs offer exciting opportunities to rethink chemical engineering workflows.