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Young, I.T. (author), El Morabit, M. (author), Liqui Lung, G. (author), Vermolen, B.J. (author)Based upon a collection of compact LEDs (light-emitting diodes) and a compact photodiode, we have developed a calibration tool for fluorescence microscopes that are used as digital imaging devices. The entire device (excluding a USB connector) measures 25 mm x 80 mm x 12 mm. Virtually all commonly-used fluorophores can be simulated with one of...conference paper 2008
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Dietrich, H.R.C. (author), Van den Doel, R.L. (author), Hoyer, W. (author), Van Oel, W. (author), Liqui Lung, G. (author), Garini, Y. (author), Jovin, T. (author), Young, I.T. (author)In previous publications we have shown that we can perform enzymatic reactions in nanoarrays by means of a microarray-reader based on a conventional microscope. In this publication we report on a modification of this system in order to monitor the aggregation kinetics of the natively unfolded protein ?-synuclein. We describe the motivation for...conference paper 2005
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Young, I.T. (author), Garini, Y. (author), Dietrich, H.R.C. (author), Van Oel, W. (author), Liqui Lung, G. (author)Traditional light sources for fluorescence microscopy have been mercury lamps, xenon lamps, and lasers. These sources have been essential in the development of fluorescence microscopy but each can have serious disadvantages: lack of near monochromaticity, heat generation, cost, lifetime of the light source, and possible distortions due to...conference paper 2004