The value of a mobile educative Application additional to Standard counselling on aspirin Adherence in Pregnancy

The value of a mobile educative Application additional to Standard counselling on aspirin Adherence in Pregnancy: the ASAP study, a randomised controlled trial

bij de Weg, Jeske M. (Vrije Universiteit Amsterdam; Amsterdam Reproduction and Development Research Institute, Amsterdam)
de Boer, Marjon A. (Vrije Universiteit Amsterdam; Amsterdam Reproduction and Development Research Institute, Amsterdam)
Meijer, Cynthia (Vrije Universiteit Amsterdam; Amsterdam Reproduction and Development Research Institute, Amsterdam)
Lugtenburg, Noëlle (Student TU Delft)
Melles, M. (TU Delft Applied Ergonomics and Design)
de Vries, Johanna I.P. (Vrije Universiteit Amsterdam; Amsterdam Reproduction and Development Research Institute, Amsterdam)
de Groot, Christianne J.M. (Vrije Universiteit Amsterdam; Amsterdam Reproduction and Development Research Institute, Amsterdam)

2024

Objective: To assess the added value of a novel, mobile educative application to standard counselling on aspirin adherence during pregnancy versus standard counselling alone. Methods: Participants were randomly assigned for additional use of a mobile educative application or standard counselling alone. Main outcome measures were adherence to aspirin measured by two validated questionnaires: Simplified Medication Adherence Questionnaire (SMAQ), Believes and Behaviour Questionnaire (BBQ), and patients reported tablet intake >90%. Results: A total of 174 women with an indication for aspirin during pregnancy were included. The questionnaires were filled in by 126 out of the 174 participants (72.4%). Similar results were found in the app group and the standard counselling groups for both validated questionnaires. Tablet intake >90% was seen in 88.7% and 87.5% (p = 0.834) of the app group and standard counselling group respectively. Subgroup analyses demonstrated a negative effect of BMI and a positive effect of educational level on adherence. Conclusions: Our study revealed no added effect of a novel, mobile educative application to standard counselling on aspirin adherence during pregnancy. Tablet intake was equally high in both groups probably explained by our high educated population. Innovation: Future studies should focus on tailored counselling on medication to pregnant women's needs including medication reminders, addressing concerns, adequate health literacy and side effects, offering rewards to further stimulate aspirin adherence in pregnancy with optimal outcome for mother and their neonate.

Adherence
Aspirin
Counselling
Education
Educative application
Pregnancy

http://resolver.tudelft.nl/uuid:478c5b9b-eb91-4d86-aa82-42d0c3af003b

https://doi.org/10.1016/j.pecinn.2024.100268

2772-6282

PEC Innovation, 4

Institutional Repository

journal article

© 2024 Jeske M. bij de Weg, Marjon A. de Boer, Cynthia Meijer, Noëlle Lugtenburg, M. Melles, Johanna I.P. de Vries, Christianne J.M. de Groot