Peroxygenase-Catalysed Epoxidation of Styrene Derivatives in Neat Reaction Media

Journal article (2019)

Authors

M.C.R. Rauch BT/Biocatalysis - AS
F. Tieves BT/Biocatalysis - AS
C.E. Paul BT/Biocatalysis - AS
I.W.C.E. Arends Universiteit Utrecht
Miguel Alcalde Institute of Catalysis, CSIC, Madrid
F. Hollmann BT/Biocatalysis - AS
Research Group
BT/Biocatalysis (AS) (TU Delft)
Copyright: © 2019 M.C.R. Rauch, F. Tieves, C.E. Paul, I.W.C.E. Arends, Miguel Alcalde, F. Hollmann
DOI: https://doi.org/10.1002/cctc.201901142
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Published Date

2019

Language

English

Reuse Rights

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Faculty

Applied Sciences

Department

BT/Biotechnologie

Research Group

BT/Biocatalysis

Abstract

Biocatalytic oxyfunctionalisation reactions are traditionally conducted in aqueous media limiting their production yield. Here we report the application of a peroxygenase in neat reaction conditions reaching product concentrations of up to 360 mM.