Print Email Facebook Twitter Recent trends in synthetic enzymatic cascades promoted by alcohol dehydrogenases Title Recent trends in synthetic enzymatic cascades promoted by alcohol dehydrogenases Author de Gonzalo, Gonzalo (University of Seville) Paul, C.E. (TU Delft BT/Biocatalysis) Date 2021 Abstract Alcohol dehydrogenases have fascinated chemists over the span of a few decades to catalyze oxidation and reduction reactions and have been increasingly incorporated as biocatalysts in scaled-up industrial processes for the production of valuable chiral compounds under mild and environmentally friendly conditions. In this review, we discuss recent advances on alcohol dehydrogenases coupled in cascade reactions with other enzyme classes, chemocatalysts, or organocatalysts to obtain high value–added products. The examples include deracemization processes for the synthesis of chiral diols and amino alcohols, whole-cell and co-expression systems, and chemoenzymatic and organoenzymatic cascades, with a vision for future developments. To reference this document use: http://resolver.tudelft.nl/uuid:8216e4de-894e-4ea8-8728-8403ef105a45 DOI https://doi.org/10.1016/j.cogsc.2021.100548 ISSN 2452-2236 Source Current Opinion in Green and Sustainable Chemistry, 32 Part of collection Institutional Repository Document type review Rights © 2021 Gonzalo de Gonzalo, C.E. Paul Files PDF 1_s2.0_S2452223621001048_main.pdf 786.6 KB Close viewer /islandora/object/uuid:8216e4de-894e-4ea8-8728-8403ef105a45/datastream/OBJ/view